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Personal Information  
Name :Lubna Swellmeen
Academic Rank :assistant professor
Office No :1403
Phone :
Department :Pharmacy
Email :lswellmeen@zu.edu.jo
CV

 
Qualifications
Bachelor : الجامعه الاردنيه Date :
Master : الجامعه الاردنيه Date :
Ph.D. : الجامعه الاردنيه Date :
Research - Journals
lubna swellmeen , Identification of Novel Inhibitors for Pim-1 Kinase using Pharmacophore Modeling Based on a Novel Method for Selecting Pharmacophore Generation Subsets., Journal of Computer-Aided Molecular Design , 10.1007/s10822-015-9887-7
12/01/2015
Targeting Proviral integration-site of murine Moloney leukemia virus 1 kinase, hereafter called Pim-1 kinase, is a promising strategy for treating different kinds of human cancer. Headed for this a total list of 328 formerly reported Pim-1 kinase inhibitors has been explored and divided based on the pharmacophoric features of the most active molecules into 10 subsets projected to represent potential active binding manners accessible to ligands within the binding pocket of Pim-1 kinase. Discovery

lubna swellmeen , 1,3-Oxazole Derivatives: A Review of Biological Activities as Antipathogenic, Der Pharma Chemica, , 8(13):269-286
08/01/2016
Oxazole is heterocyclic five membered rings that have been investigated in the development of novel compounds with promising therapeutic activities. Therefore, these compounds have been synthesized as target structures by many researchers and were evaluated for their biological activities. In this review, we report the structures of 1,3- oxazole with their corresponding biological activities as antipathogenic agent.

lubna swellmeen , ANTIMICROBIAL SCREENING OF NOVEL N-4-FLUOROPHENYLQUINO- [7,8-b][1,4]-BENZODIAZEPIN-3-CARBOXYLIC ACID DERIVATIVES, Revue Roumaine de Chimie , 60(9), 899-905
04/01/2015
New 6-fluoro-4,12-dioxo-4,7,12,13-tetrahydro-1H-quino-[7,8-b][1,4]-benzodiazepine- 3-carboxylic acid derivatives with N-4-fluorophenyl substitution were prepared and characterized for the first time. In-vitro antimicrobial screening of targets and related intermediates revealed that the quino[7,8-b]benzodiazepines targets 11a-c have shown good antibacterial activity against gram positive strains whereas other intermediates (9 and 10) are having stronger and broader spectrum of activity. Co

lubna swellmeen , Structure based drug design of Pim-1 kinase followed by pharmacophore guided synthesis of quinolone-based inhibitors, Bioorganic & Medicinal Chemistry 2 , 5 (17), 4855-4875
07/01/2017
Abstract Over expression of Human Phosphatidyl inositol mannoside kinases isoform 1 (Pim-1 kinase) has been reported in several leukemia and solid tumors. Our continuous interest to reveal the secrecies of the mysterious Pim-1 kinase binding pocket has led us to employ a structure based drug design procedure based on receptor-ligand pharmacophore generation protocol implemented in Discovery Studio 4.5 (DS 4.5).

Conferences
Synthesis And Biological Screening OF Novel 3-(carboxymethyl)-10-Alkyl-5-fluoro-2,7-dioxo-1,2,3,4,7,10-hexahydropyrido[2,3-f]quinoxaline-8-carboxylic acid and Acyclic Precursors
?A.Corbella?? International summer school on Organic chemistry-Italy-2015
Italy
2015.01.01
The reaction of 7-chloro-1-alkyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (7) with each of DL- Aspartic acid and L- Aspartic acid afforded the corresponding 2-[(3-carboxy-1-alkyl-

Experiences
pharmacist
worked as in patient and outpatient pharmacist in King Hussein Cancer center for 5 years dispensing drugs and preparing chemotherapy for cancer patients